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KMID : 0381219700020090077
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Journal of RIMSK
1970 Volume.2 No. 9 p.77 ~ p.79
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POSTINFECTIOUS INTRAVASCULAR THROMBOSIS WITH GANGRENE AFTER PENICILLIN INJECTION
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Abstract
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Cyanosis, hemorrhagic bullae and gangrene on buttock, extremity and lower abdominal wall following intramuscular penicillin injection in children with infectious disease are a rare condition, and "postinfectious intravascular thrombosis with gangrene" has been applied for this disease entity.
The mechanism is still unknown, but many authors have explained that a diffuse vasculitis with arterial spasm-intraarterial thrombosis-hemorrhage-gangrene are principal.
At this time, injection of penicillin may act as a trigger mechanism in the evolution of an underlying allergic vascular disease.
We experienced 2 case under one year of age.
One patient. died of concurrent severe pneumonia´ and one patient losed right foot due to dry gangrene.
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KEYWORD
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